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Double-Cycle high Dose Chemotherapy with Autologous Hematopoietic Stem Cells and Immunocytes Transplantation in Refractory Non Small Cell Lung Cancer
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Abstract:
We treated 8 patients with refractory non small cell lung cancer by the method of double - cycle high dose chemotherapy with actwated autologous bone marrow, peripheral stem cell, and immunocytes trnsplantation which takes four months. Regimen consist of cyclophospamide 3600mg/m2, adriamycin 90mg/m2 , cisplatin 150mg/m2, and etoposide 900mg/m2 given in three days. The results showed that all the treated patients hematopoietic function recovered in twenty five days after transplantation and some of the patients' immune function recovered more quickly. 3 patients were abtained complete responses , 3 patients partial responses, and 1 patient no change 1 patient died after the double cycle treatment. This research suggests that usage of high dose chemotherapy can improve the treating effect of refractory non small cell lung cancer. It is necessary for the patient with disease to use the double cycle transplantation treatment. The treatment is safe.
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Clc Number:
R979.1 R735.2
