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Archive > Volume 7 Issue 4 > 2000,7(4):273-274. DOI:10.3872/j.issn.1007-385X.2000.4.009 Prev Next

Cytotoxicity of GS and IL-2 Activated PBMC to Malignant Glioma Cells

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    Abstract:
    Objective: To investigate a new method for improving the therapeutic effect on malignant glioma. Methods: A new type of killer cells, named GS-LAK, was induced by means of costimulating the peripheral ginsenoside(GS) and in-terleukin-2 (IL-2). Comparing with control group-LAK cells, cytotoxicity of GS-LAK cells against malignant glioma cells(BT325) was examined with MTT method. Results: It showed that GS-LAK cells exhibited some advantages over LAK cells in proliferation, cytotoxicity, as well as the utilizing of IL-2. Conclusion: The application of GS-LAK cells might open a new prospect to clinical therapeutic approach to malignant glioma.

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