Both the mechanisms and responses of tumor immunotherapy are different from those of the traditional therapy. Therefore, whether the traditional clinical response criteria are suitable for assessing the efficacy of immunotherapy is worth exploring. First, whether the immune response should be included in the response criteria of immunotherapy? Secondly, how to determine the time point for evaluating the efficacy of immunotherapy? Thirdly, which indices should be included for the new immune-related response criteria of tumor immunotherpay? Immunotherapy is showing an increasingly important role in clinical therapy of tumor, and it is of great significance to establish a scientific response criterion system for the development and clinical application of tumor immunotherapy.
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Project supported by the National Natural Science Foundation of China (No. 30872986/H1611)