Mobile website
Expert Forum
Recent advances in the research on immune microenvironment of glioma
- Article
- Figures
- Metrics
- Preview PDF
- Reference
- Related
- Cited by
- Materials
Abstract:
Glioma is one of the most common primary tumors in the central nervous system. Given the presence and unique immune characteristics of the blood-brain barrier, investigations of the relationship between the immune microenvironment of the brain and glioma development are particularly important. In recent years, significant advances have been made in the research on: (1) changes in the immune microenvironment in physiological and pathological states of the brain, (2) the function of various immune cells and immune molecules in the local microenvironment of glioma, (3) the relationship between local immunosuppression and glioma growth, and (4) the regulation and intervention of the glioma immune microenvironment in light of potential treatment of glioma. The aim of this paper is to review these advances.
Keywords:
Project Supported:
The National Nature Science Foundation of China (No. 91229110, No. 81273215), and the Key Projects of Science and Technology Commission of Shanghai (No.13JC1407700)
Clc Number:
