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Precise medicine and individualized diagnosis and treatment of bladder cancer
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Abstract:
Bladder cancer is one of the most common malignant tumors of urinary system. It has been more and more difficult to diagnose and treat bladder cancer with old clinical models. Neo-biomarkers and actionable targets emerge with the incoming big data such as TCGA (the cancer genome atlas), MSK-IMPACT (Memorial Sloan-Kettering-integrated mutation profiling of actionable cancer targets),and HPA (human protein atlas) etc, providing more sufficient and reliable basis for the precise diagnosis, treatment and prognosis of bladder cancer. Precision medicine systems based on clinical data and omics information will be applied to the clinic more widely.More investment from government, lower cost and the constant development in new techniques represented with NGS (next generation sequencing) and liquid biopsy all make the precision medicine available from bench to bed, which will provide patients with more accurate and effective diagnosis and treatment. Here, we mainly summarize the development of precision medicine and its study and clinical application in bladder cancer.
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