The application and perspectives of organoids in tumor research
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Abstract:
[Abstract] Over the last few decades progress in the field of stem cell biology makes a new kind of 3-D human cells in vitro culture techniques available, which is termed organoids because of its space structure similar to organs. Organoids derived from tumor tissues largely retained the biological characteristics of tumor tissue in vivo, and both the advantages of low cost and easy operation make up the defects of the previous conventional cancer models. Organoids can also be used for translational medical research, formulating individual therapeutic schedules including drug sensitive tests, and combining with many kinds of technologies. This article focus on the application and prospects of organoids in tumor research.
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Project supported by the National Science Foundation of China(No.81672892)