Project supported by the National Key Technology Research and Development Program of China (No. 2015BAI12B12), the Joint Research Fund for Overseas Chinese,Hong Kong and Macao Scholars (No.31729001), the General Program of National Natural Science Foundation of China (No. 31570877,No. 31570908), and the Special Funds for Conditional Construction and People's Livelihood Science and Technology of Jiangsu (No.BL2014034)