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Archive > Volume 27 Issue 8 > 2020,27(8):835-842. DOI:10.3872/j.issn.1007-385X.2020.08.001 Prev Next
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Genetic counseling and precise diagnosis and treatment strategies for lung cancer
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Abstract:
Environmental factors are important risk factor for lung cancer. Smokers are 20 times more likely to develop lung cancer than non-smokers. However, less than 20% of smokers develop lung cancer. In recent years, many studies have shown genetic polymorphism plays an important role in the development of lung cancer, mainly involving single nucleotide polymorphisms and rare highexogenous mutations. The in-depth research of the gene polymorphism will be beneficial to the screen of susceptible genes in lung cancer and genetically high-risk population, providing genetic counseling and evidence for clinically precise diagnosis and treatment. This article mainly summarizes the contents regarding genetic susceptibility of lung cancer and high-risk population screening, early diagnosis of lung cancer as well as precise medication of advanced lung cancer.
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Project Supported:
Project supported by the Project of Chimeric Antigen Receptor (CAR) Immune Cell Technology Research and Development from the Department of Finance of Jilin Province (No. 2018SCZWSZX-010), the Science and Technology Development Project of Department of Science and Technology of Jilin Province (No. 20190303146SF), the Special Project of Development and Reform Commission in Jilin Province (No. 2017C022), and the Key Laboratory Construction Project of Department of Science and Technology of Jilin Province (No. 20170622011JC)
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