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Archive > Volume 28 Issue 8 > 2021,28(8):769-774. DOI:10.3872/j.issn.1007-385X.2021.08.001 Prev Next
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Practice of precision oncology: targeting the tumor immune microenvironment
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Abstract:
In recent years, the development of tumor immunotherapy technology has made great contributions to broadening the field of precision tumor medicine. The immune microenvironment, which is an important factor that affects the treatment efficacy of immunotherapy, plays an indispensable role in tumor progression and mobilization of anti-tumor immunity. Immunity radiotherapy, immune checkpoint inhibitors, tumor vaccines, immune cell therapy, and other methods for the tumor immune microenvironment have achieved many results in clinical research, but their clinical efficacy still needs to be improved. This review introduces the composition and characteristics of the tumor immune microenvironment and expound the feasible optimization strategies for the current treatments targeting the immune microenvironment from the perspective of clinical application.
Keywords:
precision oncology ; tumor immune microenvironment (TIME) ; cancer immunotherapy
Project Supported:
Project supported by the National Natural Science Foundation of China (No. 81930080)
