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Archive > Volume 30 Issue 3 > 2023,30(3):187-195. DOI:10.3872/j.issn.1007-385X.2023.03.001 Prev Next
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Mechanism and respone strategies of resistance in tumor immunotherapy
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Abstract:
Immunotherapy is a major strategy of antitumor therapy, whereas it still faces many challenges in clinical application. Although a large number of studies have revealed numerous mechanisms for the occurrence of immunotherapy resistance, it is still the tip of the iceberg in the face of the complex immune microenvironment. How to determine the main mechanisms of immunotherapy resistance in different tumor types and developing efficient strategies for reversing immunotherapy resistance are key issues that need to be addressed in the field of current tumor immunotherapy. Systematically discuss the research progress of immunotherapy resistance mechanisms and response strategies, in order to provide new ideas for better clinical understanding of the process of immunotherapy resistance and discovering novel reversal strategies.
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